BME 5902 Special Topics: Cellular Neurophysiology

This course examines the biophysical concepts of synaptic function with the focus on the mechanisms of neural signal processing at synapses and elementary circuits. The course combines lectures and discussion sessions of primary research papers. Topics include synaptic and dendritic structure, electrical properties of axons and dendrites, synaptic transmission, rapid and long-term forms of synaptic plasticity, information analysis by synapses and basic neuronal circuits, principles of information coding, mechanisms of learning and memory, function of synapses in sensory systems, models of synaptic disease states such as Parkinson and Alzheimer´s diseases. Additionally, a set of lectures will be devoted to modern electrophysiological and imaging techniques, and modeling approaches to study synapses and neural circuits.